Sustanon 250

Sustanon ‘250’ contains 4 esters of testosterone with different duration of action. The esters are
hydrolysed into the natural hormone testosterone as soon as they enter the general circulation.
A single dose of Sustanon ‘250’ leads to an increase of total plasma testosterone with peaklevels of approximately 70 nmol/L (Cmax), which are reached approximately 24-48 h (tmax) after
administration. Plasma testosterone levels return to the lower limit of the normal range in males
in approximately 21 days.
Distribution
Testosterone displays high binding (over 97%) to plasma proteins and sex hormone binding
globulin.
Biotransformation
Testosterone is metabolized to dihydrotestosterone and oestradiol, which are further
metabolised via the normal pathways.
Elimination
Excretion mainly takes place via the urine as conjugates of etiocholanolone and androsterone.
INDICATIONS
Androgen replacement therapy for confirmed testosterone deficiency in males.